The museum was established under the name "Cuza Vodă" Museum, on the basis of the collections of V. A. Urechia and Paul and Ecaterina Paşa, respectively. The building housing the museum was built between 1937 and 1939. The exhibition includes archaeology items: Palaeolithic artefacts found at Pleşa, Puricani, Şipote, Neolithic artefacts (Criş culture); the votive altar from Şendreni, Roman and mediaeval objects, history finds; ethnography items: costumes, fishing tools, a loom, fabrics, a library (8,000 books). The museum owns goods listed in the National Cultural Heritage Treasure.
|307||"Costache Negri" Memorial House||Galaţi||Costache Negri||Costache Negri||Memoriale||Map it|
|1678||Collections House Museum||Galaţi||Galaţi||Strada Eroilor nr. 64 (Clădirea fostei farmacii Ţinc)||Istorie||Map it|
|1628||"Prince Cuza House" Museum||Galaţi||Galaţi||Strada Al.I.Cuza nr. 80||Memoriale||Map it|
|1679||"Hortensia Papadat Bengescu" Memorial House||Galaţi||Iveşti||Iveşti||Memoriale||Map it|
|1680||Rural House "Ioan Avram Dunăreanu"||Galaţi||Rediu||Suhurlui||Etnografie||Map it|