The museum was established based on the private collections of Mihai Dimitriu and Constantin Solomon, in a building donated by Teodor Cincu. Until 1934, the museum was housed in the building of the local commercial high school. In 1934, the museum acquired the archaeology collection from Mihai Dimitriu, the first custodian of the institution, and a coleoptera collection belonging to Professor Alecu Alesînschi (lost after the 1965 reorganization). In 1974, the museum heritage was enriched by archaeological finds coming from the campaigns of 1926 - 1951 undertaken by Professor Radu Vulpe and Mrs Vulpe in the site of Poiana-Nicoreşti (Piroboridava) until then kept in the deposits of the Bucharest Institute of Archaeology. The present building is a monument of architecture built in the second half of the 19th century. The exhibits include pottery from Neolithic (axes, knives, hand mills, and pottery belonging to Cucuteni and Criş cultures), from the Bronze Age (Monteoru culture pottery), the Iron Age (food vessels); jug bearing god Dionysius' mask, Dacian ornaments and weapons deposits (4th - 3rd centuries BC), the gilded bronze hoard of Callatis (3rd century BC), glass pot bearing a Greek inscription (4th century AD) etc.
The museum owns goods listed in the National Cultural Heritage Treasure.